Saccharomyces_A

Both a and mating pheromones elicit an arrest of cell

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Unformatted text preview: y cannot signal to a mating partner; others are sterile because they cannot respond to a signal. A simple test enables one to distinguish between the two. Both a and mating pheromones elicit an arrest of cell division in the receptive cell type. If one places a patch of cells of one mating type on a patch of cells of the opposite mating type, a zone of growth inhibition appears where the pheromone from one cell type has caused the arrest of division of the other cell type. Sterile mutants that produce no zone of growth inhibition either fail to secrete mating pheromone or they secrete mating pheromone but are unresponsive to pheromone from the opposite cell type (Fig. A.14). Cells Respond to the Binding of Pheromone Through a Signal Transduction System By analyzing mutants that are sterile but still synthesize pheromone, yeast researchers identified many components of the signal transduction systems through which cells respond to the binding of pheromone at their surface. Plasma membrane receptors at the cell surface mediate the pheromone response. a cells produce -phe...
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This note was uploaded on 10/03/2013 for the course BI 206 taught by Professor Celenza during the Spring '08 term at BU.

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