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Unformatted text preview: es. Eventually the minimal ploidy needed for survival was reduced to the haploid state. The genome was left, however, with the remnants of the ancient duplications and still retains many duplicated genes scattered around the genome. Figure A.6 shows a map of the yeast genome with 53 pairs of otherwise nonhomologous chromosomal segments identified as having been originally 5 derived by duplication. Yeast geneticists estimate that about 15% of all yeast proteins are encoded by duplicated, unlinked genes. Examples of duplicated genes include gene pairs that code for transcription factors, translation factors, protein kinases, contractile proteins like myosin and tubulin, the cyclins, the histones, and the mating pheromones. Tools of the Yeast Geneticist Yeast is a powerful system for classical mutant isolation and characterization as well as systematic whole genome analyses using genome data and microarrays. Several techniques of yeast genetics enable researchers to answer questions that are difficult, if not impossible, to resolve in other orga...
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This note was uploaded on 10/03/2013 for the course BI 206 taught by Professor Celenza during the Spring '08 term at BU.

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