Unformatted text preview: a particular pattern of gene expression, trigger the differentiation pathways that generate
a, , and a / cell types in yeast. Mating between a and a
cells is directed by another genetic program. Research has
shown that the mechanisms for cell communication, the
control of gene expression, and the differentiation of cell
types are based on the same principles in yeast and multicellular, higher eukaryotes.
What we learn from yeast will very likely tell us a
great deal about ourselves. Mounting evidence suggests that similar proteins in yeast and humans carry out most
cellular processes. It also indicates that human genes
closely related in sequence and function to the regulatory
genes of yeast play similar regulatory roles in human cells.
Geneticists have already sequenced the entire yeast
genome and thereby produced a comprehensive catalog
of more than 6000 gene functions required to make a eukaryotic cell.
In the next genetic portrait (Portrait B), we move from
the differentiation of single-celled eukaryotes to the development of multicellula...
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- Spring '08
- DNA, MAT locus, Yeast Geneticist