Saccharomyces_A

The receptors contain seven noncontiguous hydrophobic

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Unformatted text preview: romone receptors, which are products of the a-specific STE2 gene. Similarly, cells produce a-pheromone receptors, which are products of the -specific STE3 gene. The receptors contain seven noncontiguous, hydrophobic domains long enough to span the lipid bilayer of the plasma membrane; as a result, each protein snakes back and forth through the plasma membrane, exposing some parts of the entire polypeptide to the cell’s exterior and others to the cell’s interior (Fig. A.15). Although the receptors are cell-type specific, the remainder of the pheromone response pathway, depicted in Figure A.15, is controlled by the haploidspecific genes, or hsg, which are expressed in both a and cells (review Fig. A.9). har06584_refA_001-020 11/4/06 10:10 AM Page 13 A.3 Mating: Cell-to-Cell Communication Through Pheromones α pheromone 13 a pheromone α-pheromone receptor (Ste2) a-pheromone receptor (Ste3) Produces Produces Plasma membrane Plasma membrane Signal transduction Signal transduction Transcription of genes...
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