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Three main themes unify our genetic portrait of yeast

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Unformatted text preview: te. Three main themes unify our genetic portrait of yeast. First, to identify the genes and proteins influencing development, researchers isolate and study mutants defective for a specific process. Second, master regulatory genes in yeast control the expression of other genes, whose activities determine the phenotype of a cell. Third, cascades of proteins called signal transduction systems (described in Chapter 19 of the main textbook) transmit the signals responsible for shifting a cell from one phenotype to another. A Yeast colonies, each containing about 107 cells, grow from single cells spread on solid media. In examining yeast as a model organism for understanding development, we present: • An overview of yeast in the laboratory: significant details of the yeast life cycle, current knowledge of the yeast genome, and basic tools for looking at yeast. • Cell differentiation: molecular mechanisms for determining cell type. • Mating: how cell-to-cell communication through pheromones promotes the conversion of haploid cells...
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