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Unformatted text preview: become a/ cells. During mating a and cells
communicate with one another through pheromones: hormones that play a role in eliciting sexual behavior. a
cells secrete a pheromone and
pheromone. Each haploid cell type carries receptors for
the pheromone of the opposite cell type; a cells carry
receptors for pheromone, and cells carry receptors for
a pheromone (Fig. A.13). When bound to pheromone, the
receptors activate a signal transduction system whose
cascade of protein interactions ultimately promotes transcription of a speciﬁc set of genes. The yeast pheromones
provide an example of how small molecules produced in
one cell type and secreted into the extracellular environment can inﬂuence the behavior of a neighboring cell.
Through the isolation of mutants, it has been possible to
dissect genetically the processes by which cells produce
and respond to pheromones.
Researchers discovered many of the genes responsible
for the pheromone response system by the isolation of sterile mutants. Some mutants are sterile because the...
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- Spring '08