Unformatted text preview: glutamate, thus preventing excitotoxicity in the neuron that is thought to cause AD. Abnormal glutamate production and stimulation is thought to produce neuronal dysfunction and cell death. With Namenda, this overstimulation is blocked and symptoms may improve. Aricept is a AChE inhibitor, which blocks the breakdown of acetylcholine. As neurons die from the disease, the amount of Ach within the synapses is reduced. Aricept blocks the metabolism of ACh thus increasing the amount and improving synaptic cell-to-cell communication and symptoms. 5) What are the risk factors for sporadic AD? Name several factors (at least 2). Age Female Apo E4 Mutation...
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- Fall '05
- Namenda, Tangles Neuritic Plaques, brain cells Tangles