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Unformatted text preview: Divide ﬁrst so they
do not run out of
cells. Differentiation Osteoblasts
change in cell
"b" for build • Cells that build bone bone formation
• Synthesize organic components of matrix
• Initiate calcification – take calcium from blood
and deposit it within matrix by exocytosis This calcium hardens, and they become trapped in the matrix
they produce, and then differentiate into osteocytes. Immature cells
Anything that ends in "cyte" is mature. Anything
that end in "blasts" are immature. Both immature and become mature when
they can differentiate into osteoclasts. Osteocytes
• Mature cells involved in maintenance of
Osteocyte with its
dendritic processes Called this because they look like nervous tissue
in the cell body. Osteoporosis, 3rd ed, Marcus, Feldman, Nelson, Rosen. Bone form and function. 2008 Osteoclasts
• Break down bone bone resorption
• Release proteolytic enzymes and acids to
degrade collagen and releas...
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This note was uploaded on 10/10/2013 for the course PSIO 201 taught by Professor Stanescu during the Fall '08 term at University of Arizona- Tucson.
- Fall '08