212_Enger-2011-09-23-stdt

Many studies have shown somatic cells can only divide

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Unformatted text preview: rized by insufficient cell divisions in the bone marrow stem cells that give rise to blood cells. Telomerase and health Important questions for current research: Does telomerase activity affect rate of aging? Many studies have shown: Somatic cells can only divide a certain number of times in culture before they die. Over-expression of telomerase allows these cells to continue dividing. Telomerase delays cellular senescence Current questions include: Can we change our telomerase levels by stress management, diet, exercise? If so, can we slow aging? To test this model: What predictions does it make? For each key prediction, can we test it? 7 9/21/10 Current questions include: Can we change our telomerase levels by stress management, diet, exercise? If so, can we slow aging? Telomerase and health Cancer Some cancer cell lines have high levels of telomerase and are released from normal growth controls. In other cases, telomere erosion may contribute to chromosomal abnormalities in cancer cells. To learn from a Nobel Laureate: http://www.ibioseminars.org/blackburn/blackburn1.shtml 8...
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