Review quiz 3 - Lectures 4-5

Review quiz 3 - Lectures 4-5 - a. Ca 2+ ions act as second...

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Choose the most incorrect answer. 1. Receptors a. The glutamate and GABA A receptors are structurally distinct. b. The pentameric nicotinic acetylcholine receptor has a total of 20 membrane-spanning domains. c. The four M2 domains of the acetylcholine receptor are important to its ion permeation properties. d. Leucine side chains line the open pore of the acetylcholine receptor. e. There is no homology between nicotinic and muscarinic acetylcholine receptors. 2. Receptors a. NMDA glutamate receptors require glycine as a co-agonist. b. AMPA glutamate receptors have fast kinetics. c. G-proteins are integral membrane proteins, but do not form ion channels. d. The alpha subunit of a G-protein is not a very efficient GTPase. e. The action of a G-protein can inhibit adenylyl cyclase. 3. Synaptic transmission
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Unformatted text preview: a. Ca 2+ ions act as second messengers during synaptic transmission. b. Following neurotransmitter release, large numbers of ion channels in the postsynaptic cell open and close almost simultaneously. c. The intracellular Ca 2+ concentration at the active zone changes significantly during an action potential. d. Choline cannot activate the acetylcholine receptor. e. EPSPs at the NMJ are much larger than those in the CNS. 4. Synaptic transmission a. Glutamate predominates at excitatory synapses in the CNS. b. Inhibiting its M-channels will make a neuron more excitable. c. NMDA receptors are essential to long term potentiation. d. Glutamate can mediate slow synaptic transmission. e. Neurons in the CNS receive predominantly either excitatory or inhibitory input....
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This note was uploaded on 04/08/2008 for the course BIO 328 taught by Professor Cabot during the Spring '07 term at SUNY Stony Brook.

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