It transports and ips the 3d structure antibody

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Unformatted text preview: t transports and flips the 3D structure. antibody invader Antibodies are large groups of proteins that recognize small molecular signals on invading organisms, etc. 04-09-13: Lecture 3 Proteins are agents of molecular specificity! Use of small molecule recognition Toxic - Can cause destruction to cell and it causes the cell to die. Many toxins are proteins that can find Target cells through binding to small molecular signals on the Target cells toxin cell outside cell A way for signals and information to Inside cell be sent and received between cells. 04-09-13: Lecture 3 Proteins are agents of molecular specificity! Big molecule recognition Protein – Protein interaction Cell recognition Structural proteins Protein receptors (e.g. insulin, endorphins) Specificity in Membrane Dynamics (e.g. endosomes, Golgi, etc) protein marker membrane compartment wrong place right place wrong place right place wrong place right place 04-09-13: Lecture 3 Proteins are agents of molecular specificity! How is Recognition Accomplished? By providing a Binding Site that favors the Molecular Target being “detected” above all others. Specificity! - with R-groups: Molecular toolbox Whole protein structure creates space - Positioned R-groups (ex. Pocket). Target Molecule 04-09-13: Lecture 3 Proteins are agents of molecular specificity! Ex. Sucrase - and enzyme the cleaves sucrose into glucose and fructose What helps sucrase recognize and bind to sucrose? 3D shape – form a binding site Enzyme cycle for Sucrase Functional groups help stabilize interactions noncovalent interactions Does sucrase prefer to bind sucrose - or glucose and fructose????? 04-0...
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This note was uploaded on 11/02/2013 for the course BIOLOGY 1 taught by Professor Traver during the Spring '10 term at UCSD.

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