Kami Export - 10 Oxidative Phosphorylation-S.pdf -...

Oxidative Phosphorylation 1
Oxidative Phosphorylation
How are the electrons in NADH and FADH
2
used to make ATP during cellular respiration?
Why?
The final phase of cellular respiration is oxidative phosphorylation . Both the electron transport chain
and chemiosmosis make up oxidative phosphorylation. During this phase of cellular respiration, all of the
NADH and FADH
2
that were produced in other phases of cellular respiration (glycolysis, the link reac-
tion, and Krebs cycle) are used to make ATP. The process occurs in the protein complexes embedded in
the inner mitochondrial membrane.
Model 1 – Electron Transport Chain
H
+
H
+
H
+
H
+
H
+
H
+
H
+
H
+
H
+
H
+
H
+
H
+
H
+
H
+
H
+
H
+
H
+
H
+
H
+
H
+
H
+
H
+
H
+
H
+
H
+
H
+
H
+
H
+
H
+
H
+
H
+
H
+
H
+
H
+
H
+
H
+
H
+
H
+
H
+
H
+
H
+
H
+
H
+
H
+
H
+
Outer
Mitochondrial
Membrane
Intermembrane
Space
Mitochondrial
Matrix
Inner
Mitochondrial
Membrane
High potential
energy electron
NADH
FADH
2
2H
2
O
NAD
+
+ H
+
FAD
+
+ 2H
+
O
2
+ 4H
+
Embedded
protein channels
H
+
H
+
H
+
1. Consider the membranes illustrated in Model 1. Circle a section of the mitochondria below
where this site might be located.

2 POGIL
™
Activities for AP* Biology
2. Refer to Model 1.
a. Describe the region in Model 1 where the highest concentration of hydrogen ion (H
+
) is
located.
b. According to Model 1, how do the hydrogen ions reach this area?
3. Explain why energy is required to move the hydrogen ions across the membrane in the direction
indicated in Model 1.