HIV_Progression_to_AIDS_Alex_Bobby_Zeb_Presentation - Predicting the Onset of AIDS Robert Arnold Alex Cardenas Zeb Russo LMU Biology Department Outline

HIV_Progression_to_AIDS_Alex_Bobby_Zeb_Presentation -...

This preview shows page 1 - 7 out of 23 pages.

Predicting the Onset of AIDS Robert Arnold, Alex Cardenas, Zeb Russo LMU Biology Department 10/5/2011
Image of page 1
Outline What causes a subject to develop AIDS from HIV and what separates AIDS from HIV? Focusing on dS/dN ratio The definition of AIDS, the subjects affected, and their similarities, ALIVE information New hypothesis involving the division of subjects into those with AIDS, trending towards AIDS, and AIDS free trending away Research comparison, proving assumptions incorrect Further comparisons between the subjects with AIDS and those without Comparing our results with our paper
Image of page 2
dS/dN ratio related to AIDS development determined that low dS/dN ratios, subjects that select either for nonsynonymous mutation or not against it were the subjects to develop AIDS The subjects picked were 4, 9, 11, and 14, all with 0.0 dS/dN ratios along with subject 10 with a 0.2 and subject 1 with a 0.3
Image of page 3
Outline What causes a subject to develop AIDS from HIV and what separates AIDS from HIV? Focusing on dS/dN ratio The definition of AIDS, the subjects affected, and their similarities, ALIVE information New hypothesis involving the division of subjects into those with AIDS, trending towards AIDS, and AIDS free trending away Research comparison, proving assumptions incorrect Further comparisons between the subjects with AIDS and those without Comparing our results with our paper
Image of page 4
AIDS and CD4 counts CDC definition of AIDS is a CD4 count below 200 Once diagnosed, cannot be reversed Makes our first hypothesis irrelevant since all ‘rapid progressors’ drop below 200, AKA all 6 have AIDS Subjects 1, 3, 4, 10, 11, 15
Image of page 5
Outline What causes a subject to develop AIDS from HIV and what separates AIDS from HIV? Focusing on dS/dN ratio The definition of AIDS, the subjects affected, and their similarities, ALIVE information New hypothesis involving the division of subjects into those with AIDS, trending towards AIDS, and AIDS free trending away
Image of page 6
Image of page 7

You've reached the end of your free preview.

Want to read all 23 pages?

  • Fall '13
  • guptaki

  • Left Quote Icon

    Student Picture

  • Left Quote Icon

    Student Picture

  • Left Quote Icon

    Student Picture

Stuck? We have tutors online 24/7 who can help you get unstuck.
A+ icon
Ask Expert Tutors You can ask You can ask You can ask (will expire )
Answers in as fast as 15 minutes