Nature 41896 99 overriding ow can reverse the lr axis

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Unformatted text preview: /R axis Axis often reversed Nonaka et al (2002). Nature 418:96-99 Overriding flow can reverse the L/R axis as often as ~50% of the time. This is similar to primary ciliary dyskenia. This also suggests nodal flow may be crucial in mammals. Model: normal flow in the node Model: nodal vesicular parcels (NVPs) transport materials to the left side of the Node. This triggers signaling there adapted from that leads to L/R asymmetries. Gilbert 9e, Fig. 8.35 Calcium is elevated on the left side of the node Gilbert 9e, Fig. 8.35...
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