5-6-13_limbs_pt_1

Buds that express both have mixed identity conclusion

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Unformatted text preview: Buds that express both have mixed identity. Conclusion: Tbx5/4 determine limb identity. Limb buds have mixed identity in limbs that express both Tbx4 & 5 FGF10 beads implanted near the wing results in buds that express Tbx4. The resulting limb is mostly winglike. Gilbert 9e, Fig. 13.7 Limb buds have mixed identity in limbs that express both Tbx4 & 5 Gilbert 9e, Fig. 13.7 FGF10 beads implanted closer to the leg result in buds that express Tbx5. The resulting limb is a combination of half wing and half leg (including feathers/scales). Limb outgrowth critically depends on the Apical Ectodermal Ridge (AER) The apical ectoderm ridge (AER) is a region of thickened ectoderm around the edge of the limb bu...
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This note was uploaded on 11/08/2013 for the course ZOOLOGY 470 taught by Professor Hardin during the Fall '12 term at Wisconsin.

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