Materials for Clotting - Materials for Clotting Doug...

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Materials for Clotting Doug Metzger When an injury occurs, be it on the playground or during battle, the most important and preliminary thing to do is to stop bleeding. With that being said, it is surprising to learn that dressings used in war today have only been marginally improved since the Civil War. 1 Even though much more advanced weapons are used today, 90% of deaths in war are people on the front line. Of that 90%, half of those people die from losing too much blood before they can be treated by a medic or surgeon. 2 Given the extreme advances in science since the days of the Civil War, there should be a practical solution to hemorrhaging. Scientists have invented multiple hemostatic bandages, one main one using biomaterials and another using a polymer. Dr. Kenton Gregory of Oregon developed a bandage using chitosan, a molecule derived from chitin, a carbohydrate found in the shells of shrimp and other shellfish. Chitosan is a positively charged molecule, so when the bandage is applied over a wound, it attracts the negatively-charged red blood cells, effectively creating a near-immediate seal on the wound, as seen in Figure 1. 1,3
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This note was uploaded on 04/07/2008 for the course MSE 182 taught by Professor Braun during the Fall '07 term at University of Illinois at Urbana–Champaign.

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Materials for Clotting - Materials for Clotting Doug...

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