L6 Antibiotics and Bacterial Resistance

Nobelprizeorg 6 from chance discovery to wonder drug

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Unformatted text preview: enhanced by chemistry •  Began working with penicillin BIOLOGY 1A03 •  Developed a brown powder that was an=bacterial for Cellular and Molecular longer than a few days Biology •  So… Fleming discovered it and Florey & Chain made it a usable product http://www.nobelprize.org/ 6 From chance discovery to wonder drug! BIOLOGY 1A03 Cellular and Molecular Biology 7 Unit 2: Bacterial cell wall synthesis Bacteria have a cell membrane & cell wall BIOLOGY 1A03 Cellular and Molecular Biology Cytosol http://sbftm.blogspot.ca 9 Structural carbohydrates- pep$doglycans Bacterial rarely produce cellulose to contribute to their cell wall - produce pep=doglycans - backbone consists of two types of alterna=ng monosaccharides with a chain of amino acids a[ached to one of the sugars BIOLOGY 1A03 Cellular and Molecular Biology http://sbftm.blogspot.ca 10 Bacterial cell walls are made up of pep-doglycans BIOLOGY 1A03 Cellular and Molecular Biology http://sbftm.blogspot.ca 11 Building bacterial cell walls- a dynamic process BIOLOGY 1A03 Cellular and Molecular Biology http://sbftm.blogspot.ca The building blocks of the cell wall are made inside the cell, then transported out...
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This note was uploaded on 11/21/2013 for the course BIOLOGY 1A03 taught by Professor Dr. kajiura during the Fall '10 term at McMaster University.

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