04_CV_Membrane_Potentials

04_CV_Membrane_Potentials - Which cell have resting...

Info iconThis preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon
1 Ionic Basis of Resting 10/5/07 Which cell have resting potentials? • All cells • All cells have similar ion concentration gradients • All cells contain K + (& Cl - ) leak channels and have a negative resting potential • Most cells (e.g. glia) only carry passive signals a very short distance Which cell have action potentials? • Some cells carry Action Potentials: –Neurons – Few others: pancreatic β cells • Called “electrically excitable” • Unique feature is presence of specialized ion channels K + K + Na + Na + Cl - Cl - Ca 2+ Ca 2+ - + + + + + + + - - - - - - What are the forces that create the membrane potential?
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
2 + Nernst Equation + + + - - - - Membrane Potential Depends on: Nernst Equation: V m = E equil = 58 log 10 [ion] out z [ion] in • Ion concentration gradient • Selective permeability of the membrane for particular ions • For one permeable ion, use the K + permeable 0 mV for no gradient K + permeable - 58 mV for 10X gradient
Background image of page 2
Image of page 3
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

Page1 / 8

04_CV_Membrane_Potentials - Which cell have resting...

This preview shows document pages 1 - 3. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online