final 2007 KEY

final 2007 KEY - BIBClZO-Final Name _[_\/_\_9‘2_E£_E§g,...

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Unformatted text preview: BIBClZO-Final Name _[_\/_\_9‘2_E£_E§g, _____________ __ w C} 7t“ 1) (50 pts) A patient comes into your office with the following symptoms: fatigue, tiny pinpoint hemorrhages on the skin, joint pain, bleeding gums and wounds that don’t heal. a) (10 pts) What is your diagnosis? (what vitamin is deficient and what is the name of this disease). 53g" Lat/Jar) Vil‘atm-i} C tie—Crai‘encj b) (10 pts) What protein in the patient’s connective tissue is defective? Why is it defective? \ __Canq Mk3; L34“)? Fall" (5 r; {W Collagen ts imaL've (Va 5 — '+ «CM «wig («th ML“ +5 H, C acessar (+1 3064‘ pwhné 0" Lyarox ’5’: l (or I; mi :9 c) (20 pts) Draw the structure of this vitamin in the re uced form. a“ .0 ‘7. for awLL ?¢nem( maxi-Aka, O : 0135‘"; “rue. 1701\4) mm CJJ’éOp‘Jg-h) I Exaryilaf +1? pal-("5 ecu— oxiJIRJ 430"», w? x % Al’LerL art 3 «FIJI/(E; J 00’)» fileJ' 4" R I oud' 'K yhun‘vra +5 fir 99,516, ring Swure d) (10 pts) What two tissues or organs need high levels of this vitamin? +5 vex“: 8965)‘flmun& $35 ) waljfamisflfolhtflj) (gratin, or +7 gr 1' LPN55 ) CIA“ +1 Igor 5 S 1 BIBC 1 20-Final Name _____________________________ __ 2) (50 pts) a) (5 pts) What is the name of the bacterium that is the #1 cause of food— borne illnesses? +5 CAMPY LOBACTBR C - Pond—s PW Misgwumjaolkfie‘amiigm b) (5 pts) Which bacterium is the most deadly in terms of the percent mortality among food—borne pathogens? Mensa! IA +5 c) (5 pts) Which virus is the most common source of GI distress among food-borne pathogens? NOROVlR-Mg mi NORWPWV— Vim” +6 (1) (15 pts) What three sectors of the population are most vulnerable to + food poisoning? , FQEGNANT WoMgN (FETUSB 0» ‘EL‘D'eFLLY 5 90M" o m Pam’s Cup 4'5 I?) o Pewue vol COMPRDM\S€'D \Mmum’rv e) (5 pts) The most severe form of food allergy (can lead to death) is called: {,9 ANAPHYL—AX\S 0a RNfiPHYLACTlC S’Hmu: f) (5 pts) What is the name of the protein that can trigger celiac disease? QLMTEN *5 g) (10 pts) Why is this protein a good elicitor of celiac disease (give two properties or aspects)? M2 *5 o Vow-1'5 of Protein am Simian: 41> dfaxzd’idI/l/not gully bWK-PM 0Lon +5 M2 " AcHVa/RS‘ ‘HM ivmvvtum S‘lS'WV‘ 0‘4- WMP‘MWW‘ 0‘2, 16E Y‘Qspo’YKSJl 3 mt MHQW restmm / BIBC 1 20-Final Name _____________________________ __ 3) (50 pts). The structure below is the modified form of a Vitamin as it is commonly found in food. uo WM C'Hz‘d” C’\/\/\/\/\/\/\/\ \ \ \ \ a) (15 pts) Draw the structure of the vitamin alone. 5H — '5 Cor ocho‘x b) (5 pts) What is the name of this particular form of this vitamin? \ ‘ 0 & cm Mo\Qw\{ aw (iii: is”; mm have, 00 \’ £0“ CCQLQWD c) (10 pts) What are the names of the other two form of this vitamin? RQXMOH (4 mas-emit.“ s) ‘ \ * 5 \o“ as as \ 944nm, OLTL QQVWCMC AQ\C\}\ m may) “a OVOJLfl; d) (5 pts) What is the upper limit for this vitamin? ScooMs/AM or SOJOOZMU cc 3600 RAE 02 01C? go( waxy; omits\ e) (10 pts) What are two conditions or problems that results rom too FD much of this vitamin? + g V k€&&\ocCK/\QAVJ«QAA\OX 410‘ hVQJ ,b‘mfiA &Q€Qd.$ (imam 9MB MGM (cuss CLQCQ tall at 3 \9 e. ‘ 0090(H6Vq? V\ 0 {owga \au J \(loss amok gfou weeds f) (5 pts) What is the condition or disease that results from a deficiency in this vitamin and that affects millions of children around the world? Lt\V\C§\/\Q%IS (at XQfo VW\MKO\B (WSW HMAMQfib 0K) ' BIBCl 20-Final Name _____________________________ __ 4) (60 pts) Sarah is a 60-year old Asian woman (postmenopausal). She exercises regularly and lives in San Diego so she sunbathes a lot. She consumes a lot of fiber in the form of wheat bran and a lot of spinach. She has been lactose intolerant all her life, so she consumes no dairy products and drinks a lot of cola. a) (50 pts) List 5 factors that affect Sarah's risk for osteoporosis, indicate whether the factor increases or decreases the risk, and explain how the factor affects the risk. \0 oomks total fix each (txth : 39*6 {ac «Patchy; 59*5 for (nu/doe, Apt“; (or e»<p\0m0th‘or\ ‘Soobotwa deg. (ask bk, pmdwws mt?) EVttDnUZc‘LQci f0? Cot“ (M050 rQh‘cfl \n s\ ._ Exercise. QUC, “SK DIR. “W3 Ddfidk bowl‘wwks5 “ Ramon ammo» me. “SK big, gemh'u predxsgosition‘ ’ KUWOOUF 801% MC, rig/z. \ac commn> phjtx‘g atom col/Mun to: C03) '5 impwfi \ib amtghon f - 5Qi‘flach me, NS»: \OIL. OcaflA‘LOtud bindsro (09* u u ‘ Loam \mdQ/(O‘V‘Q'tno (La/Ct inc. risk; \olc. (mart/3 (igngou(cQ OE . —\ .. _ + ,c (QM so mg“ \‘thhwd (02+ Missal?) 4mm we)? ago? 04.0}meer inc, risk \o/q, (‘QSUl‘kg in reduced bone, Aerial?) 00er MMhOQQNSL.. me. rm bit low QWOQ‘W‘ aboma L033 - R%Q’ Ma, ((84 big. (HWWCMDMQJ Oxc‘QQ/{Ql-OU‘QQ 800% K383 i n 9 9 l b) (10 pts) If blood calcium drops below 8.5 mg/ d1, what two hormones or signals does the body release to increase blood calcium levels? W D (5 as) Poxoxfngmid her mom (5 9V3» BIBC 1 20-Final Name _____________________________ __ .2 E $(sng mispQM-Ld x - r r ++vw WANG?“ “"3 5) (65 pts) :2; i, g “Hm "ox—ii waffle“ [disusL/ Two obN'WOV‘S a) (20 pts) Give the name of a isease caused by a Vitamin B defIC1ency (you pick one) and give two conditions or diseases caused by this deficiency. Indicate which B Vitamin is deficient for these conditions. d B‘ (Tl/Mimi") ’Ecri - Wk) 1mm) 0QWHAQ‘HC, {0S5 0‘6 MQJ’VUSVYJ WW6 9' {lmHflwe ) 6M3 QM gf‘AVLCJ’rO") g; CFIUWIA> a éq‘bggizh-g __ :nfiqmmtc’ hvtflvw,’ slNOHQl/l g3 (menx— pg“_9,5‘('0\ ~— Wolwzt skin} Li D‘s b) (20 pts) Give the name of a second disease caused by a different Vitamin B deficiency and give two conditions or diseases caused by this deficiency. Indicate which B Vitamin is deficient for these conditions. EL ‘ W 41 lt‘S'i’ otme OovNulsst} dLMWI’IZHS or uwlum $1MY>+UMS of We 64? ‘H/LUAA - 41 wt q __ M‘olus-hc (1th #7 4/220 1 4/03,) ‘V‘ ‘7”; $5 94me C83 6Pfl‘n; “({3de A ka WW 4005M!» clog-{j bun/I”) or Lurk W W‘"& am .— mafitli‘fii“ a NEW} imam PM W c) (5 pts) Wthh B Vitamin is used in transamination reactions? B e /]>\l(l.A/O)LD\.( d) (20 pts) Draw the structure of this Vitamin as it would appear in the middle of a transamination reaction (i.e. the structure of the reaction intermediate). Include the structure of a possible substrate in this reaction intermediate. 73: o , \ ,wlofVWi‘L‘r 1‘ m»; gnaw—Lou} S S‘ ‘ 5" S W H0\ / /CHLOH 3 WW"? '6; ' swirwa )\ ' tofu c5?+s \N ’1 f0” ekda bsdeo/Ieiwzyfl’ inwfldy '6 Jr‘ 3 3 bwslelmw‘s Wm” H 5 F? owl—Na, puff wmg —?D FF §=FM+ of vabs'imi-t ‘5 a at w 13¢ smut/c mgr aim 0+ An 6 _\5 {tr {Awmvk viJrle‘s/l / BIBC 1 20-Final Name _____________________________ __ 6) (60 pts) a) (15 pts) What are the BMI ranges for people for the following classes: obese: over 30 (no upper Yum") 57.5 points given r? on: 435 \mrcmgc 'VW cam overweight: 26- BO (ZS/N 01°33.) mass .‘S C Owe up. normal: ‘35- 96 (‘3'$_ 1L1 0W7 b) (15 pts) Have obesity rates been increasing or decreasing over the past 2 decades? Give two general reasons for this. in dredging —- +Do (mm m lecow 3W6 am not mouam ecu Cflpmdlrhxe. (Wt enough exorcise) c) (10 pts) What two other ways beside BMI are used to assess obesity? blo b00155 ’tcod' and “01% 37% d) (10 pts) Give two severe conditions or diseases that result from too much abdominal adipose tissue. Com-Passe d dams _ No CXch‘l’ '- beam was (or mm) (nape—res dwarfiw Cantor N: do madam, namrnc -(inc\ud1f\5 it b\oo<\ Vega? w Mum e) (10 pts) Defigne thermic effect of food. W hwwm‘s‘m doygw\\rt acous W— 115?me 0? energy mcdch-k-o di9€s+-€>od. BIBCl 20-Final Name _____________________________ _- 7) (55 pts) a) (5 pts) Is the incidence of type 2 diabetes increasing at the same rate or faster than the increase in population? $.56» figs?“ b) (10 pts) Whataarg two major risk factors for type 2 diabetes? +43» so“, :vae5‘w J y‘be 5\\{ccw‘c wage can». wst—P—i‘aw ' excelch krsch (fitwwxs/ b0 MW CdAW‘ie— ‘tvu—oUO 9—. m c) (15 pts) What are three typical characteristics of type 1 diabetes that distinguish it from tyng? V d“?- 9—91‘ ::wzha.ra.¢\—u‘\"zh‘¢$ 03" VL" 435%" I 5‘! “PM”; ________,_..__ 64, HR, Wew-k' a,u.éL biological of)? em 0‘4" ths-ca—ec . WWW utJJ‘l— ~ stale “cat gamma/Bar. d) (15 pwmmmfifditiogs%r typewz diabetics that doctors try to remedy by medications or exercise? “i”? tor '0»; CM‘VTOvts glow/A oVL stifle, fiywbw’: t s A e) (10 pts) Dr. Edelman explained how one form of diabetes can progress into the other form. Explain how this happens. Jr: cw; Twez —=~> W? m {eefihncc lauds *Lb/faxm. \hSuCi‘Vt *0 4°”?ensklt W cow -— Loci/“P? W3 bum F6 Mu) 54'” BIBC 1 20-Final Name _____________________________ __ 8) (60 pts) a) (20 pts) Explain how mineral iron enters the absorptive cells of the small intestine given that it starts in the lumen of the intestine. Give the names of any barriers and which mineral form crosses a barrier more readily. b l Barriers m {/0005 law 4/ F‘dsm“ W m (+s) 0+5) Few cmésos mum/5 Fats-Feb (+55 WQJQZQ 095.965 'Flas ma W5W(+:) b) (10 pts) Give two factors that promote absorption of mineral iron. G5) vc+mtnc (is) 1 (Warm .4ch 63;) 24mm)“ $6 c) (5 pts) \Aél‘ulat is tilgupper limit for iron? Pb FHA Cred/(.1. Lf 5/7992! (+5”) ‘6'”? a 6+ 4*) d) (15 pts) If the body accumul tes too much free iron in the blood, what {m M is the harmful reaction that can occur that generates free radicals (give P” the name and write out the reaction). (Fes4'4/«z0; J; Paulo #10 {r' C +8 EAR Fenw WW 6+3) (“raw—Wufi) Fe” 1/ {4,0, ——»Eafi+ 0 H10“. e) (10 pts). What is the most name of the toxic p duct produced by the reaction in part (d)? Why is it so toxic (what is the nature of the product that makes it so toxic and what critical macromolecules does it harm in the cell)? 1407.!9 P11" “bl-l" _, “animal 04" 3) ‘P.r-h‘al chHrG’Z: ever‘cr (\cao‘HI/e/ WW} Mia/mammflgw/c (Prol—c‘m / Vipr nods/{L was) BIBClZO-Final Name _____________________________ __ 9) (50 pts) a) (15 pts) In the Atkins diet you reduce consumption of carbohydrates and increase consumption of protein. Even if you obtain protein from beneficial sources, what three physiological complications can occur? +5 '- Lfihscmfleh +3 ’- LoaRSue 1‘ 6003 Ni’rfoosevx 0:! $He$$ on k33nexjg T “10 \ogs ke’ros'xs of Hmong hoaxes 9f Mata 51003 +0‘ twp , Loco/ Hob (M *0 2: ’ Que: (m We \oenQRQaA b) (5 pts) What is the RDA level for carbohydrates needed to prevent Sov’wsb these complications? {LDASWJOfl/gwj c) (15 pts) If one’s dieting progresses to bulimia, what are the complications that can result (give 3). ‘ 4—51 3mm okra/s +7. 3 (51 AME +0Vh esophks°$ ,i W ewc b bohmiov +00?“ depths A903,“ SP 144+ gkemm __ , ' gwef be 0N9 “he '/ - (ta/ax“ “(Nb \- (m5 unwile cm 8 \g 9‘} d) (5 pts) What organ in the brain contains the centers that control appetite and satiety? \MWOWN WS e) (10 pts) If surgery is needed to deal with weight gain, what is available? Give an example by giving the name of the surgery and a brief description of what it does. +\0'v ESASWOODMH' (ash/\ch owcexg 0‘6 @008 Jro 63% ab HM). Stw_ Gibb/e3 Swat/kc. low-$53 —— Yes’w'sdv Row 41mm QSOPhcgsug im-o 3mm”. WF‘V‘O‘Q (3093M; \oxfiaxgs— Q'wvxk $003 Waugh M (piece 46 $1: M bhoocsses \Mosi— ab 4M9 Stom‘ Mask ’1, +0 ’5 4°“ 3M¢om6>\e+e/ivxm{/ed aescéxaoléorx — gmweg +\ +0 +3 Loy 3e¥al\\e3 sesm‘mm ob wwle'xpVE Swfiefiefl _ 4"0 'u \RfOSUKfVQK ,W"S MSW} (39.4) V)" VA" . 1 0 ...
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This note was uploaded on 04/07/2008 for the course BIBC 120 taught by Professor Crawford during the Spring '08 term at UCSD.

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final 2007 KEY - BIBClZO-Final Name _[_\/_\_9‘2_E£_E§g,...

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