bicd 140 mt

bicd 140 mt - Name _ Student ID # _ BICD 140 Spring 2007...

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Name __________________ 1 Student ID # ___________ BICD 140 Spring 2007 Midterm Exam #1 Please write your name on each page and look through your exam. It should have 9 pages. Do not use pencil or white out on your exam. Be certain that all of the work that you want graded is written in permanent ink. Your score Multiple choice, 29 points possible ________ True/False, 18 points possible ________ Short answer I, 14 points possible ________ Short answer II, 12 points possible ________ Short answer III-IV, 14 points possible ________ Short answer V, 13 points possible ________ Total possible 100 points. ________ Graded exams will be distributed after class as soon as they are graded. If you will not pick up your exam then, you may sign below to signify that you have given your permission for your exam to be distributed in a way that may subject it to public scrutiny. If you sign below your grade will be posted by student ID on the website so that you may check your recorded grade. Signature_____________________ I pledge not to cheat, plagiarize, steal, or lie in matters related to academic work. Signature_____________________
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Name __________________ 2 Use your scantron to indicate the correct answers for questions 1-. Choose from the following antibody isotypes to fill in the blanks using your scantron. The Question number is indicated by each blank (1 point each): a) IgG b) IgD c) IgA d) IgE e) IgM Naïve B cells primarily express 1) __E ___ (which is pentameric when secreted) and 2) __B ___ on their cell surface until they become activated. After activation, B cells produce a variety of antibodies that all have unique functions. The antibody isotype first secreted during an immune response is 3) __E ___ _ . Commonly found in bodily secretions, 4) _ _C__ ___, can provide newborn babies with some immunological protection because it can be transmitted through breastfeeding. The Ig called 5) __D_ __ is often coated on the surfaces of mast cells and can contribute to hypersensitivity diseases. One of the most abundant antibodies in the body, 6) _ __A_ ___ is critical for providing the lasting humoral protection that results from vaccination. The antibody called 7) __D___ is important for combating intestinal parasites such as tapeworms. Multiple Choice. 1 point each. Choose the one answer that best fits the statement/question. 8) Which of the following does NOT involve the irreversible recombination of the somatic genome? a) V-region assembly from gene fragments b) Isotype switching c) Somatic hypermutation d) Synthesis changes from membrane-bound Ig to secreted Ig e) They are all irreversible. 9) The Toll-like receptor signaling pathway relies on many protein complexes including: a) MHC b) MyD88 c) IRAK d) b and c e) all of these 10) Secondary lymphoid tissues include all of the following except: a) Spleen b) Peyer’s Patches c) Thymus d) Tonsils e) All of these are secondary lymphoid tissues 11) The diversity of the third hypervariable region (aka CDR3) in immunoglobulins is due to
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This note was uploaded on 04/07/2008 for the course BICD 140 taught by Professor Goldrath during the Spring '07 term at UCSD.

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bicd 140 mt - Name _ Student ID # _ BICD 140 Spring 2007...

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