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Unformatted text preview: reaction which required template DNA, dNTPs and DNA polymerase to replicate the DNA. a. Name three other enzymes which are missing from this simple picture and explain their function in DNA replication. b. What are dNTPs? c. DNA replication proceeds in the 5 to 3 direction. Draw the mechanism for how a dNTP is added to the 3 end of the strand. d. For the following replication fork, draw the leading and lagging strands. 5. What is the cause of DNA supercoiling during DNA replication? What enzyme relieves this supercoiling? 6. As a protein involved in DNA repair in a human skin cell, you and your family are responsible for identifying mismatched bases. 5 GGCTAGT 3 3 CCGGTCA 5 a. For the above DNA helix, how can you determine which strand of the helix contains the incorrect base? b. Answer this question if instead you worked in prokaryotic cells....
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- Fall '08