Problem_Set8, bimm 100

Problem_Set8, bimm 100 - polysome formation? Why or why...

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BIMM100 Fall 2008 Problem Set 8 1. Translation allows the formation of polypeptide chains. a. What are the tRNA binding sites in the ribosome? Describe each site. b. Once the ribosome is formed, what are the mechanisms which ensure that the correct tRNA (with the correct amino acid) will bind to a given codon? c. What is the molecule responsible for catalyzing the formation of a peptide bond? How does it participate in the formation of a peptide bond? Does this step require GTP (if not, where does the energy come from)? d. Describe the process of translation termination. How is eRF1 able to bind to the A site of the ribosome? e. What is a polysome? Would the loss of the exon junction complexes have any effect on
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Unformatted text preview: polysome formation? Why or why not? 2. You are a veterinarian studying a virus which attacks chickens. This virus will infect chicken cells, which then produce viral proteins until the host cell dies. You remember from molecular biology class that many antibiotics are able to kill bacteria because they inhibit protein synthesis. Can you use similar antibiotics to kill the virus infecting chickens? Explain. 3. RNA world hypothesis a. Explain why it is unlikely that the first primitive cells had the central dogma? b. Why is it likely that RNA was around before DNA? Why do we have DNA as the main form of genetic information storage?...
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This note was uploaded on 01/10/2009 for the course BIMM bimm 100 taught by Professor Dr.sato during the Fall '08 term at UCSD.

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Problem_Set8, bimm 100 - polysome formation? Why or why...

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