2.8 Module 2 Part 3 Notes for Blackboard SN2

For two nucleophiles with the same nucleophlic atom

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Unformatted text preview: α carbon: methyl > 1° > 2° (NOT 3°) 6 Bases versus Nucleophiles •  Bronsted bases react with protons •  Nucleophiles react with other electron- deficient (δ+) atoms 7 Nucleophilicity mirrors basicity in these 3 cases 1.  For two nucleophiles with the same nucleophlic atom, the stronger base is the stronger nucleophile O NH Weaker base Weaker Nu vs NH 2 Stronger base Stronger Nu 8...
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