Day 8 Notes Key.pdf - sciovirtual.org Functions \u25cf Protect against injury and infection \u25cb Keratin waterproof barrier \u25cb pH is acidic(5.5 \u25cb Sebum

Day 8 Notes Key.pdf - sciovirtual.org Functions u25cf...

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sciovirtual.org Functions Protect against injury and infection Keratin - waterproof barrier pH is acidic (5.5) Sebum and sweat are antimicrobial Defensin - acidic protein Langerhans cells - immune cells Regulates body temperature Sweat Vascular constricts and expands Sensory perception Regulates water loss sweat Chemical synthesis Keratinocytes Aka skin cells Joined by desmosomes (adhesive protein complex) Keratinocytes in stratum corneum become corneocytes (no nucleus or organelles) Corneocytes joined by corneodesmosomes Keratin Fibrous structural protein Makes up skin, hair, nails, feathers, scales, etc. (wow!) Alpha - keratin is only type present in humans keratin type I (acidic) and keratin type II (basic) join together to form keratin intermediate filament Give skin, hair, and nails its strength! Melanocytes In stratum basale Produces melanin from tyrosine Melanin prevents UV DNA damage (UVC is most harmful) Everyone has same # of melanocytes Eumelanin - black and brown tint Pheomelanin - yellow and orange tint
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