Day 5 Notes ANSWER KEY - sciovirtual.org Day 5 Notes Muscle physiology Sliding Filament Model 1 2 3 4 Sliding Filament Model \u200bprocess used to aid

Day 5 Notes ANSWER KEY - sciovirtual.org Day 5 Notes...

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sciovirtual.org Day 5 Notes Muscle physiology Sliding Filament Model - Sliding Filament Model: process used to aid muscle contraction 1) ATP is hydrolyzed 2) Energized myosin binds to actin (formation of a crossbridge) 3) Power stroke occurs, leading to the release of ADP + P i 4) ATP binds to myosin, decreasing its affinity for actin - Rigor Mortis: When a person dies, they stop producing ATP. At the same time, the calcium channels in the sarcoplasmic reticulum become leaky, leading to an influx of Ca 2+ in the cell. This Ca 2+ binds to the troponin complex of the thin filament, initiating cross bridge cycling. However, since no/minimal ATP is present in order to dissociate the actin from the myosin, they are “stuck” in this conformation. Neuromuscular Junction 1) Action potential propagates down the motor neuron 2) After reaching the end of the motor neuron, it stimulates voltage gated Ca 2+ channels to open, leading to a calcium influx 3)

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