BIO 203 Lecture 20

BIO 203 Lecture 20 - Lecture 20 Renal Physiology continued...

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Lecture 20 Renal Physiology continued Reabsorption continued: Diffusional o Proximal tubule, water will always move with solute, because when solute moves, it creates a concentration gradient, but water dissolves that gradient Regulation of secretion o Involves concentrating a solute in the filtrate in a level greater than in plasma o Transport against a concentration gradient – active o Potassium and hydrogen ion regulation Regulation of reabsorption of sodium and water o Preservation of blood volume – dilute urine – losing blood volume o Kidneys can only conserve fluid, not expand or restore volume o Na+ reabsorption is an active process o Water reabsorption is by osmosis and will follow Na+ reabsorption o Water is never actively transported o Doesn’t move if there is no concentration gradient, but if there is a gradient, water will flow, osmosis o Sodium and water reabsorption can be independently regulated o Proximal tubule – sodium goes and water follows o Distal convoluted tubule and collecting duct – sodium and water independently regulated o Water movement can only occur if epithelial cell membranes are permeable o Permeability is high in proximal tubule o Proximal tubule water and sodium are reabsorbed in constant proportions o ADH regulates water reabsorption o
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BIO 203 Lecture 20 - Lecture 20 Renal Physiology continued...

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