CHP6 The Intugumentary System

epidermis 3 stratum granulosum 3 5 layers of flat

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Unformatted text preview: amp; travel to epidermis • Engulf foreign agents to move them to bloodstream Epidermis (cont.) Epidermis 3. Stratum granulosum= 3-5 layers of flat keratinocytes 3. Stratum 3-5 that contain coarse, dark staining keratohyalin granules keratohyalin • Granules bind w/ intermediate filaments of cytoskeleton to Granules produce ‘keratin’ produce • Keratinocytes make membrane-coating vesicles Keratinocytes (containing a glycolipid) that are released by excytosis to H2O-proof skin • Tight junctions also contribute to H2O retention of skin • Glycolipid forms a barrier btw upper & lower skin layers • Separation of living and dead/dying keratinocytes between Separation stratum spinosum & stratum granulosum stratum • Cells in stratum granulosum undergo apoptosis Epidermis (cont.) Epidermis Epidermal water barrier~ • Lipids secreted by keratinocytes + tight junctions + thick tight layer of insoluble protein on inner surfaces of plasma insoluble membranes membranes • Critical for H2O retention & preventing dehydration 2. Stratum lucidum= thin translucent zone, typically only 2. Stratum thin seen in thick skin • Keratinocytes densely pac...
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