CHP5 Histology

fibrous 6 cell types fibroblasts macrophages

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Unformatted text preview: tilage & bone Tendons, less • ‘white fibers’ as tendons or in fresh ‘meats’ Reticular- thin collagen coated w/ glycoprotein • Spongy framework for spleen, lymph nodes Elastic- thinner, branching fibers of elastin (coiled structure) • Allow skin, lungs, arteries to recoil • Fresh fibers are ‘yellow fibers’ Fibrous tissues (cont.) Fibrous 6 cell types= fibroblasts, macrophages, leukocytes, plasma cells, mast cells, adipocytes Fibroblasts- llrg, flat cells w/ tapering ends; produce fibers & rg, matrix matrix • Inactive cells= fibrocytes Inactive fibrocytes Macrophages- llrg, wandering phagocytic cells that destroy rg, bacteria, foreign particles, dead cells bacteria, • Activate immune system (in presence of antigens) • Arise from WBC’s (monocytes) Leukocytes (WBC’s)- travel to c.t. & reside w/in until Leukocytes travel recruited to bloodstream recruited • ‘Neutrophils’ wander searching for bacteria • Dense patches of ‘lymphocytes’ iin mucus membranes n attack bac/toxins/foreign agents Fibrous tissues (cont.) Fibrous Plasma cells- synthesize antibodies • Specialized lymphocytes that detect foreign agents & then Specialized synthesize antibodies synthesize Mast cells- particularly along blood vessels, secrete heparin particularly heparin (anticoagulant) & histamine (dilates bld vessels) histamine Adipocytes- llrg, round cells storing triglyceride rg, triglyceride • Small clusters in fibrous tissue or dominate area (adipose Small tissue) tissue) Fibrous tissues (cont.) Fibrous 3 classes of molecules form ground substance~ • Glycosaminoglycans, proteoglycans, adhesive glycoproteins • Absorbs compressive forces, protects from mechanical injury Glycosaminoglycan (GAG)- llong polysaccharide of amino ong sugars & uronic acids sugars • - charged, so attracts Na+ & K+ & absorbs H2O • Regulates H2O/electrolyte balance • Chondroitin sulfate (most abundant form) in bld vessels, bones, & cartilage (stiffness) Glycosaminoglycan (GAG)- Heparin (anticoagulant) & Glycosaminoglycan Heparin hyaluronic acid (lubricates joints, vitreous humor) hyaluronic Fibrous tissues (cont.) Fibrous Proteoglycan- huge brush-like molecule w/ protein core & huge GAG outgrowths GAG • Forms thick colloids (‘gel’) that slows spread of pathogens • Embedded in plasma membranes, attach to cytoskeleton Embedded inside & extracellular molecules outside inside • Create structural bonds btw cells/extracellular Create macromolecules & help to hold tissues together macromolecules Adhesive glycoproteins- bind all tissue components bind together, guide migrating embryonic cells to destination together, • Protein-carbohydrate complexes that bind plasma Protein-carbohydrate membrane proteins to collagen & proteoglycans outside cell membrane Loose connective tissue Loose Types of loose & dense connective tissue grouped by Types loose dense abundance of fibers abundance Areolar tissue- lloosely organized fibers, bld vessels, & oosely ‘empty’ space ‘empty’ • All 6 cell types; collagen (mostly), elastic, & reticular fibers All randomly arranged randomly • Highly variable in appearance; serous membranes (loose Highly arrangement) –vs- skin & mucous mem’s more compact arrangement) • Almost every body part has areolar tissue; surrounds bld Almost vessels & nerves; responsible f...
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