Manufacturing Technical Paper

Pga or poly glycolic acid is one of the most

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Unformatted text preview: rial used in the manufacturing of a TE scaffold depends on numerous factors including intended application and, scaffold processing techniques to be employed [15,16]. Among all types of materials, polymers offer great potential in design and processing of TE scaffolds [17,18]. Polymers are long chain molecules of high molecular weight made up of a number of small repeating units linked together by covalent bonds [9]. Apart from the requirements listed above for scaffolds, the degradation rate of the material is also very much important to see if it matches with the growth rate of the new tissue [19]. PCL or polycaprolactone is a common biocompatible and biodegradable aliphatic polyester with low melting point and good solubility in most solvents. This material has been used in various biomedical devices, such as urethral catheters, drug delivery systems, resorbable sutures, and has been proposed as a material for engineering of bone and cartilage [20]. PGA or poly (glycolic acid) is one of the most widely used scaffolding polymers. PGA degrades rapidly in aqueous solutions or in vivo because of its relatively hydrophilic nature. It loses mechanical integrity between two or four weeks. The most widely used scaffold designs made from this polymer are the nonwoven fibrous fabrics [9]. PLA or poly (lactic acid) is another widely used polymer for s PROTOTYPING TECHNOLOGIES The technologies reviewed in this paper are the 3- Dimensional Printing, Fused Deposition Modeling, and Electrospinnning. 3.1 Limitations of Conventi...
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This note was uploaded on 01/14/2014 for the course MECH 810 taught by Professor Various during the Fall '13 term at Queens University.

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