{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}


Selec2ve interac2ons raymond ahlquist 1948 epinephrine

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: s … eventually USA: Johns Hopkins Hospital, first real “research- oriented” med school Pharmacology’s Big Idea The receptor concept - major challenge at the 2me was to make medicine less dangerous, and more effec2ve - enter the scien2fic method - first chemical structures in the 1860’s John Langley (Cambridge, 1878): first postulated the idea of ‘recep2ve substance’ using nico2ne and curare analogs on muscle contrac2on Paul Erhlich (Frankfurt, Langley contemporary) had a great interest in specificity, & furthered the receptor concept, showing that stereospecificity was cri2cal to drug- receptor signaling… distribu2on vs. selec...
View Full Document

{[ snackBarMessage ]}

Ask a homework question - tutors are online