sedation restlessness motor problems extrapyramidal

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Unformatted text preview: lly involved • 10% relapse in low EE homes • 58% relapse in high EE homes   First Generation Antipsychotics  • Block Dopamine Receptors • Thorazine (1954), Haldol • Reduces + & disorg. Sx • Little effect on neg. Sx • 30% do not respond favorably 2 12/9/13 SECOND-GENERATION ANTIPSYCHOTICS  • Clozapine (1988): + , disorganized Sx Agranulocytosis: drop in white blood cell  count • Also: drooling, weight gain, fatigue • Increased risk for diseae related...
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This document was uploaded on 01/16/2014.

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