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Unformatted text preview: s w/ motor cortex
as well medial prefrontal! Wraps around corpus
collusum anterior cingulate!
The PFC is a huge area in the human brain. And it is broken up into functional distinct
areas.Important b/c underlying different executive functions The Evolution of the Prefrontal Cortex!
Tiny PFC! Cats
are dumb little
animals with tiny
cortexes. Huge expansion of PFC in human brain; more than any other area. V1 is comparatively
smaller than other species, other areas are comparable. A Model of Cognitive Control in the Prefrontal Cortex!
“Schematic diagram of some of the extrinsic
and intrinsic connections of the prefrontal
cortex. The partial convergence of inputs from
many brain systems and internal connections of
the prefrontal cortex (PFC) may allow it to play
a central role in the synthesis of diverse
information needed for complex behavior. Most
connections are reciprocal; the exceptions are
indicated by arrows.” ! Miller & Cohen (2001) An integrative
theory of prefrontal cortex function.
Annual Review of Neuroscience.! Mechanisms of Cognitive Control!
Selection of Task-Relevant Information!
Monitoring and Error Detection!
Inhibitory Control! Working Memory! Single cell recordings from monkeys in the
dorsolateral prefrontal cortex during the
delay period of a working memory task.! cue! delay! response! Keep info on online, short-term. Keep info online when you need it, but when you don't it goes away.
Working memory task is a typical design in animal studies. Monkey must keep in mind where they the food
was. Associative memory task is very different -- Monkey has to learn that the food is associated with a symbol.
May require another task in the in the delay period, and the monkey just has to be able to recall that the food is
going to associated with that object. The monkey doesn't have to keep in mind where the food is because
they've already built that association in their long-term memory between the food and that cue. Associative...
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- Fall '11