Problems in Pregnancy notes

Problems in Pregnancy notes - Biology 80A Problems in...

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Biology 80A Problems in Pregnancy Three of one type of chromosome Disorder Incidence (frequency) Usual Characteristics 18 trisomy 1:3; 300 Mental deficiency, growth  Edwards Syndrome 13-15 trisomy 1:5, 500 Mental deficiency Patau’s syndrome Sloping forehead Bilateral cleft lip and/or Palate polydactyly 21 trisomy 1:600 Mental deficiency, flat nasal   Down Syndrome bridge protruding tongue Congenital heart defects Teratogens Associated Malformation Androgenic agents (androgens) masculinization of female fetuses -labial fusions  -clitoral hypertrophy Antitumor agents Aminopterin skeletal defects    Anencephaly-lack of brain Malformation of nervous system Methotrexate multiple malformations  esp. skeletal Thalidomide Limb malformations Cardiac and gastrointestinal (gut)  Malformations Infectious Agents Cytomegalovirus Microcephaly, severe mental retardation Rubella Cataracts, deafness, congenital heart defects Toxoplasma gondii Microcephaly, chorioretinitis (eye defects)
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Problems in Pregnancy notes - Biology 80A Problems in...

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