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Product(s) Hormonal Control of
Metabolism .22 Release Hormone Action
Modulation of Enzyme Activity 4.23 How an Adrenergic Hormone Works:
An example of a "Second Messenger"
Norepinephrine Plasma Membrane Receptor
ATP Cyclic AMP Protein Kinase
(Inactive) 5' AMP Protein Kinase (Active) Phosphorylase b
(Inactive) Phosphorylase a
(Active) Synthase I
(Active) Synthase d (Inactive) « Binding of hormone to the receptor results in formation of Cyclic AMP (2nd Messenger). « The activation of protein kinase 1) activates phosphorylase and 2) inactivates glycogen synthase. 4.23 .24 How Steroid Hormones Work
Translocation H H
H H Cytoplasmic
Response How Hormones Using Ca++Calmodulin as a Second Messenger Work .25 Plasma Membrane Hormone Receptor
Entry Calcium release
from organelles Cytoplasmic Ca++
Enzyme 4.26 The Sympathetic Nervous
System & Catecholamines
Nerves NorEpi Adrenal
(20%) Various Effects Depending on Organ Acetyl Choline Vascular Smooth
(skeletal m.) .27 Control of Hormone Secretion: Insulin The secretion of all hormones is modified by a number of factors which either increase or decrease release into the b...
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This note was uploaded on 01/20/2014 for the course KIN 3515 taught by Professor Nelson during the Fall '09 term at LSU.
- Fall '09