KIN 3515 biochemistry

KIN 3515 biochemistry - Competencies q q q q q q metabolism...

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Basics of Bioenergetics
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Competencies Explain the importance of ATP in metabolism. Explain how enzymes work.  Discuss the importance of enzymes in regulating  metabolism. Explain how the intracellular concentration of  chemical modulators affect enzyme activity. Explain how hormones influence enzyme activity. Define Catabolism Anabolism Endergonic Reactions Exergonic Reaction Coupled Reactions Reversible and Irreversible Reactions Oxidation-Reduction Reactions
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Enzymatic control of metabolism Endocrine (hormonal) control of  metabolism organization of the endocrine  system specificity of hormones second messengers regulation of hormone levels Important hormones Growth hormone Thyroid hormones Catecholamines  (Sympathoadrenal System)   Adrenaline  (Epinephrine)   Noradrenaline  (Norepinephrine) Cortisol Insulin Glucagon Types of Chemical Reactions The Mole Concept Introduction to energy transfer  hermodynamics energy conversions biological work Control of energy transfer mass action effect enzymes coenzymes Biological energy transfer       Phosphate bond energy Centrality of Adenosine  Triphosphate Competencies
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Biopsy School
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'The machinery of  the body is all of  a chemical kind. It  will be expressed  some day in  physical and  chemical terms.'  A rchibald  V ivian  Hill,  (1927) 4.1
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4.2 Units of Measure tera giga mega kilo hecto deca Prefix Factor Symbol Prefix Factor deci centi milli micro nano pico femto atto 10 12 10 9 10 6 10 3 10 2 10 1 10 -1 10 -2 10 -3 10 -6 10 -9 10 -12 10 -15 10 -18 T G M k h da d c m μ n p f a Symbol
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4.2b Units of Measure 0.3938 in/cm 1.0567 qt/L 0.0022 lb/g F= C(1.8) + 32 2.54 cm/in 0.9463 L/qt 453.6 g/lb C=0.5556(F-32) length volume mass temperature Dimension centimeter (cm) liter (L) gram (g) degree Celsius (C) Metric Unit Conversions
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Fat   9.0 kcal/g Carbohydrate  4.0 kcal/g Protein  4.0 kcal/g Energy Content of  Carbohydrate, Fat, and Protein 4.3
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4.4 Anabolic Processes putting molecules together to make  bigger molecules      amino acids  -------->    proteins          glucose ---------------> glycogen Metabolism The sum of chemical  processes Catabolic Processes breakdown of fuel molecules to make  energy    e.g., breaking down glucose Bioenergetics The processes by which energy is  made and consumed by living things
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Introduction to Chemical Reactions 4.5 General Form Reactants                      Products     A + B  -------------->   C + D Endergonic Reactions energy must be added for reaction  to occur products have more energy than  reactants e.g., ADP + Pi + Energy -----> ATP
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Introduction to Chemical Reactions 4.6 6CO 2  + 6H 2 O Total Amount  of Energy  Released Free Energy C 6 H 12 O 6 Exergonic Reactions give off energy
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