Which of the following represents a next generation

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Unformatted text preview: Using genetic engineering a graduate student mutated both copies of the RNaseIII enzyme Drosha. Which of the following pathways are likely to be inactivated? a. microRNA pathway b. siRNA pathway c. piRNA pathway d. snoRNA pathway e. a, b and c 32. Which of the following pathways are dependent on the Argonaute family of proteins? a. microRNA pathway b. siRNA pathway c. piRNA pathway d. snoRNA pathway e. a, b and c 33. Which of the following small RNAs can silence genes without cleaving the target RNAs? a. microRNAs b. siRNAs c. piRNAs d. snoRNAs e. a, b and c 34. Which of the following are true regarding piRNAs? a. Are encoded in large clusters in a small number of locations in the genome b. Are made up of highly repetitive sequences c. Are needed to silence mobile genetic elements (transposable elements) d. Are dependent on PIWI for cleaving transposon RNAs e. All of the above 9 35. Which of the following technologies can measure genome ­wide expression of genes? a. Microarrays b. RNA ­seq c. ChIP ­seq d. a and b e. a and c 36. Which of the following technologies can measure genome ­wide transcription factor binding at promoters? a. microarrays b. RNA ­seq c. ChIP ­seq d. a and b e. a and c 37. Which of the following is essential for the Sanger sequencing method? a. ddNTPs b. dNTPs c. ATP sulfurylase d. a and b e. a an...
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This document was uploaded on 01/18/2014.

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