Lecture1 - CHE/BME 489 Biochemical Engineering Lecture 1...

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CHE/BME’489:’Biochemical’ Engineering’ Lecture’1’ Introduc=on’ 1/16/2013’
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Instructor’and’TA’ Instructor:’ ’ ’ Pin’Wang’ ’’ [email protected] RTH’509’ Office’hour:’ ’ Monday,’6:00’pm’to’8:00’pm’ or’by’email’appointment’ TA: ’ Chupei’Zhang’ [email protected] ’ RTH-515’ TA’office’hour:’ ’ To’be’determined’
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Text’book’ Required text: ’ Modern’Biotechnology:’connec=ng’innova=ons’in’microbiology’and’ biochemistry’to’engineering’fundamentals’by’Nathan’S.’Mosier’and’ Michael’R.’Ladisch’ Supplemental sources: Bioprocess Engineering ,’2 nd ’edi=on’by’Michael’Shuler’and’Fikret’Kargi,’ Pren=ce’Hall’2002’ Bioreac.on Engineering Principles ,’3 rd ’edi=on’by’John’Villadsen,’Jens’Nielsen’ and’Gunnar’Liden,’Springer’2011’ Biochemical Engineering Fundamentals ,’2 nd ’edi=on’by’Bailey’and’Olllis,’ McGraw-Hill,’New’York’1986’ Biochemical Engineering ,’by’Blanch’and’Clark,’Marcel’Dekker,’1996’ Molecular Biotechnology ,’3 rd ’edi=on’by’Click’and’Pasternak,’ASM’Press,’2003’ Basic Biotechnology ,’2 nd ’edi=on’by’Ratledge’and’Kris=ansen,’Cambridge,’2001’ Molecular Cell Biology ,’5 th ’edi=on’by’Lodish,’Berk,’Matsudaira,’Kaiser,’Krieger,’ Sco±,’Zipursky’and’Darnell,’W.H.’Freeman’and’Company,’New’York,’2003.’
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Course’outline’ Lectures’ Lecture’Topics ’ Chapter’ ’ Key’Dates ’ Notes’ 1’(01/16) ’ Introduc=on’to’biochemical’engineering; Microbial’fermenta=on ’ 1&4’ 2’(01/23) ’ Model’of’cell’growth 5’ Team’assembled ’ HW#1’out ’ 3’(01/30) ’ Aerated’bioreactor,’modeling’oxygen’limited’growth 6’ Topic’chosen ’ HW#1’due ’ RA#1’out ’ 4’(02/06) ’ Metabolic’basis’of’oxygen’limited’growth,’bioproducts 6&3’ RA#1’due ’ HW#2’out ’ 5’(02/13) ’ Enzyme,’enzyme’kine=cs ’ 7&8’ HW#2’due ’ RA#2’out ’ 6’(02/20) ’ Metabolism’ 9’ RA#2’due ’ HW#3’out ’ 7’(02/27) ’ Bioenerge=cs’ 10’ HW#3’due ’ RA#3’out ’ 8’(03/06) ’ Metabolic’pathway ’ 11’ RA#3’due ’ 9’(03/13) ’ Mid-term’exam ’ 10’(03/27) ’ Overview’of’recombinant’technology 2’ Case’presenta=on ’ HW#4’out’ ’ 11’(04/03) ’ Metabolic’engineering ’ 12’ Case’presenta=on ’ HW#4’due ’ RA#4’out ’ 12’(04/10) ’ Biotechnology’in’the’informa=on’age 13’ Case’presenta=on ’ RA#4’due ’ HW#5’out ’ 13’(04/17) ’ Gene=c’technique ’ 14’ Case’presenta=on ’ HW#5’due ’ RA#5’out ’ 14’(04/24) ’ Directed’evolu=on’;’Protein’engineering Case’presenta=on ’ RA#5’due ’ 15’(05/01) ’ An=body;’Protein’therapeu=cs ’ Case’presenta=on ’ 16’(05/08) ’ Case’study’report’due
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