Unformatted text preview: dual ions, we use the Nernst equation, which is given by: RT
C E = −2.3
log10 i zF
Co At 37°C, this equation simplifies as follows: ⎛C ⎞
−60 mV E=
log10 ⎜ i ⎟ z
⎝ Co ⎠ For ion A+: ⎛ 50 mEq ⎞
−60 mV
EA =
log10 ⎜
= −60 mV ⎝ 5 mEq ⎟
⎠
+1 Similarly, for ion B2+: ⎛ 0.01 mEq ⎞
−60 mV
EB =
log10 ⎜
= 60 mV ⎝ 1 mEq ⎟
⎠
+2 B. If the overall membrane potential at steady state is  40 mV, estimate the value of the equilibrium potential of C . (10) Solution: To the find the equilibrium potential of C , we need to use the chord conductance equation: g
g
g
g Em = A EA + B EB + C EC + D ED gT
gT
gT
gT From the table, we know that the equilibrium potential of D is 0 mV since the intracellular and extracellular co...
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 Spring '13
 SanjayKumar
 Orders of magnitude, Torr

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