Hence ga g g ea b eb c ec gt gt gt 1 15 25 40

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Unformatted text preview: dual ions, we use the Nernst equation, which is given by: RT C E = −2.3 log10 i zF Co At 37°C, this equation simplifies as follows: ⎛C ⎞ −60 mV E= log10 ⎜ i ⎟ z ⎝ Co ⎠ For ion A+: ⎛ 50 mEq ⎞ −60 mV EA = log10 ⎜ = −60 mV ⎝ 5 mEq ⎟ ⎠ +1 Similarly, for ion B2+: ⎛ 0.01 mEq ⎞ −60 mV EB = log10 ⎜ = 60 mV ⎝ 1 mEq ⎟ ⎠ +2 B. If the overall membrane potential at steady state is - 40 mV, estimate the value of the equilibrium potential of C- . (10) Solution: To the find the equilibrium potential of C- , we need to use the chord conductance equation: g g g g Em = A EA + B EB + C EC + D ED gT gT gT gT From the table, we know that the equilibrium potential of D- is 0 mV since the intracellular and extracellular co...
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This note was uploaded on 01/22/2014 for the course BIOE 110 taught by Professor Sanjaykumar during the Spring '13 term at University of California, Berkeley.

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