Bio151 Sp13 Exam 1 answer key

Explain your reasoning two points for each questionone

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: d TFa. No, this doesn’t explain this observation. Firstly, this doesn’t explain why gene expression is occurring without TF activation. It also doesn’t make sense that proteolysis of unphosphorylated TFa is occurring to any great extent since it’s unphosphorylated TFa that we’re seeing. B. There is a mutation in TFa that causes it to be active even when not phosphorylated. Yes, this would explain why we’re seeing expression of the skin differentiation genes when two of the signaling components are not phosphorylated. It is certainly possible that a mutation in TFa is causing it to be active even when not phosphorylated and this would explain why gene expression is occurring even though TFa isn’t getting phosphorylated. C. Two phosphatases are activated by TK1 - one targets TK2 and the other targets TFa. No, this doesn’t explain this observation. Although this might explain why TK2 and TFa aren’t phosphorylated, it doesn’t explain why gene expression is occurring without TFa being phosphorylated and activated. D. There is another signal transduction pathway that targets the same genes that has been activated. Ye...
View Full Document

This note was uploaded on 01/21/2014 for the course BIO 151 taught by Professor Randallphillis during the Fall '12 term at UMass (Amherst).

Ask a homework question - tutors are online