Lvh initiallyconcentrichypertrophywall

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Unformatted text preview: ECG; almost 30% on echocardiography Due to pressure overload on the heart Involves neuro -hormonal responses of the reninangiotensin system Heart: Left Ventricular Heart: Left Ventricular Hypertrophy ACE inhibitors – block LVH Initially concentric hypertrophy –↑ wall thickness without increase ↑ in cavity volume Adaptive response eventually fails ⇒ dilatation of ventricles and heart failure LVH is an independent risk factor that increases the risk of CVD Regression of LVH may occur with aggressive BP management Heart: Systolic & Diastolic Heart Dysfunction Systolic Dysfunction Diastolic Dysfunction Reduced LV contractility ⇒ reduced ejection fraction ↑wall thickness ⇒ impaired relaxation ⇒ ↓LV filling May be picked up early on echocardiogram Both may lead to symptomatic heart failure Heart: Coronary Heart Disease Heart Hypertension is the largest risk factor for CHD Mechanisms Acceleration of atherosclerosis in the coronary arteries Impaired endothelial function Limited coronary flow reserve Manifestations Angina pectoris, acute MI, sudden death Heart: Congestive Heart Failure Heart State in which the heart is unable to pump enough blood to meet metabolic needs of the body Hypertension is the major preventable factor in CHF Due to systolic or diastolic dysfunction or Heart Coronary Disease CHD Kidneys: Chronic Kidney Disease & Kidneys Renal Failure Arteriosclerotic lesions of afferent & efferent arterioles & glomerular capillary tufts...
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