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Unformatted text preview: ntifiable cause Secondary Identifiable cause Causes of Secondary Causes
Activating symp N.S. Drug-induced or related causes e.g. NSAIDS Chronic kidney disease Recurrent kidney infection Primary aldosteronism Reno-vascular disease Narrowing vessels change renin/aldosterone sys Chronic steroid therapy and Cushing’s syndrome Pheochromocytoma Coarctation of the aorta Thyroid or parathyroid disease Sleep apnea Absence spontaneous breathing Excess cortisol production Clinical Features
Clinical Most often asymptomatic
Reported symptoms – more likely due anxiety from knowing that they have a serious illness [Kaplan, 2002]
Headaches Dizziness Lightheadedness Tinnitus – “ringing” in the ear Epistaxis – may actually occur due to ↑
BP Some causes of secondary hypertension have definitive symptoms / signs
Other symptoms due to target organ Pheochromocytoma
Pheochromocytoma Common cause, tumour adrenal gland ↑BP (catecholamine secretion) Classic triad: hypertension, headache, excessive generalized sweating
Palpitations and tachycardia Pallor / flushing Anxiety & Nervousness Weight loss Dizziness / fainting Cushing's Syndrome
Excess cortisol production fr. tumour pituitary gland ATCH induce adrenal gland Truncal obesity / generalized obesity
Moon face Buffalo Hump
Hirsutism Excessive growth of hair
Purple Striaearea thin skin, visible BVs
Diabetes /Glucose Intolerance
Menstrual Irregularities / Impotence Target Organ Damage
Target Organ Damage Brain Eyes Stroke and TIA Transient Ischaemic Attacks
Hypertensive Retinopathy Heart Left ventricular Hypertension Systolic & Diastolic Dysfunction Coronary Heart Disease Heart Failure Target Organ Damage
Target Organ Damage Kidneys Chronic Kidney Disease and Renal Failure Blood Vessel Peripheral Arterial Disease Abdominal Aortic Aneurysm Aortic Dis...
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This document was uploaded on 01/10/2014.
- Winter '14