Pancreatic exocrine secretions exit here 2 pancreatic

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Unformatted text preview: t and Defense System 1. Pancreatic exocrine secretions exit here 2. Pancreatic endocrine secretions go into the blood (Digestive enzymes) (insuline, etc) The parenchymal view of the pancreas… 1. blue/green portion = pancreatic islet 3. Digestive enzymes go to lumen of small intestine 2. Red =capillaries (blood) 4. same view= hstology 7 02/02/2012 The stromal view of the pancreas… Islet (endocrine) how do these islets communicate and whats all that? Q.There is only 1 Islet of Langerhans on this field of view – how do islets within the pancreas synchronize their actiivity???? Brown histological stain for ' trypsinogen' (pro- form of digestive enzyme) (exocrine tissue) Is inactive by being in a pro form brown = cholinergic neurons How do cells within the individual pancreatic islet synchronize their activity? red = fibrollast cells brown= E-cadherin protien brown= macrophages aggressive immune cells they do move a lot its part of a family facilitates gap junction formation 8 02/02/2012 Diseases and disorders of the pancreas Pancreatitis – acute, chronic Diabetes – Type 1, Type 2 Exocrine Pancreas Insufficiency Cystic Fibrosis Pancreatic Cancer Pancreatic Steatosis create gap junctions Why can't the local support and defence system prevent/manage these? 9...
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