Unformatted text preview: esses go on at all
times, ie. in the presence,
and absence, of what we
think of as ‘food’ in the tube.
4 What happens to GI tract when you sleep 2 15/02/2012
Second brain- enteric nervous system The general structure of the GI ‘tube’ – and it has it’s own nervous system! 1. this single cell layer separates
the inside and outside of the
body (intestinal epithelium) the second brain also innervates the mucosa The GI ‘tube’ has unique properties…
It is about 28 ft. long – thus it has to be folded extensively in
the abdominal cavity
It has a luminal surface area of between 200 400 square meters
– thus the invagination depth/ villus microvillus height and
densities of the mucosal layer are extensive in certain zones
Has a highly variable ‘transit time’ for an ingested meal with a
marker ( 30 80 hours) of which around 5 8 hours is for normal
passage through the stomach and small intestine.
Senses and expels noxious substances – diarrhea and vomiting
Continuously interacts with the resident gut microbiome
* consisting of bacteria, archaea, and small eucaryotes and pro...
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- Winter '11
- Digestive System, GI Tract, internal anal sphincter, peripheral clocks