Unformatted text preview: t interrupts the synthesis pathway, preventing serotonin from being produced.
And serotonin, of course, is a necessary ingredient for healthy mood.
This finding may be particularly relevant for depressed patients taking selective serotonin reuptake inhibitors (SSRIs). A
study by Charles Nemeroff, MD, PhD, of the University of Miami, and colleagues suggests that depressed people who
experienced an adverse event in early life may be less likely to respond to SSRIs than depressed patients who did not
endure an earlylife stressor (Proceedings of the National Academy of Sciences, 2003). That makes sense if an
overactive immune response is working against serotonin in the brain, Pace says. "If inflammation really is driving that
problem, then something like isn't going to be as effective...
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