Toaddressthelackoffunctionaldiversityinproteinstructur

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Unformatted text preview: elow
 and
 any
 other
 reagents
 that
 you
 know,
 please
propose
a
synthesis
of
the
target
molecule.
 
 CO2 O 
 O 
 Br OH 
 O 
 O HO Br OH H+ O O Br O Mgo O O MgBr C O O O O O H2O H3O+ O OH 
 
 
 
 O 
 Problem
 #5.)
 Hemiketals
 can
 be
 formed
 under
 both
 basic
 and
 acidic
 conditions
 while
 ketals
 require
 acidic
 conditions
 for
 their
 formation.
 
 Starting
 with
 acetone,
 provide
 a
 mechanism
that
explains
this
observation.
 
 
 O H O R O- 
 H O H3O+ -O H O H2O H HO OR O R OR R OR H2O OR H O H+ RO OR R RO- RO OH 
 In
the
acid
catalyzed
case,
the
alcohol
can
be
protonated...
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