Poxvirus III Polyomavirus Lecture 13

Poxvirus III Polyomavirus Lecture 13

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Unformatted text preview: recognized in 1841 • Normally causes an inconsequential illness in infants that resolves on its own in a week to several months. • Causes 2-5 mm skin papules, (tiny, dome-shaped bumps that eventually develop a central depression) on various parts of the body. • Illness may be more sever in immunocompromised individuals • Estimated to be prevalent in 20% of people with AIDS • Virus is not widely studied • of 182 potential ORFs 105 have variola homologs A Newly Emerged Poxvirus • Caused by a member of the Orthopoxvirus genus and named Araçatuba • Isolated from skin lesions on dairy cows and milkers in Brazil • More related to vaccinia virus than any other Orthopoxvirus • Hypothesized that it is an “escaped” vaccinia virus virus Polyomaviruses (Small DNA Tumor Viruses) • Taxonomic Classification • Characterization of Virion • Infection, Replication and morphogenesis Polyomaviruses Virus Polyomavirus (Pyv) Simian virus 40 (SV40) BK virus (BKV) JC virus (JCV) K papovavirus (KPV) Hamster papovavirus (HaPV) Lymphotropic papovavirus (LPV) Simian agent 12 (SA12) Rabbit kidney vacuolating virus (RKV) Stump-tailed macaque virus (STMV)...
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This document was uploaded on 01/26/2014.

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