Poxvirus III Polyomavirus Lecture 13

Giulio eckburg 2004 lancet infect dis 415 25 monkeypox

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Unformatted text preview: spreads in a centrifugal pattern African child with disseminated monkeypox. Giulio & Eckburg (2004) Lancet Infect. Dis. 4,15-25 Monkeypox Infection Enlarged lymph nodes Giulio & Eckburg (2004) Lancet Infect. Dis. 4,15-25 Monkeypox Outbreaks Giulio & Eckburg (2004) Lancet Infect. Dis. 4,15-25 US Monkeypox Outbreak Giulio & Eckburg (2004) Lancet Infect. Dis. 4,15-25 US Monkeypox Outbreak Giulio & Eckburg (2004) Lancet Infect. Dis. 4,15-25 Cowpox • A member of the Orthopox genus • Found Mainly in Eurasia • Identified on the teats of cows • Can be transferred to humans but no documented human-to-human transmission • Human infection can range from localized to a relatively severe rash • Studies indicate that rodents are main reservoir • Cats play a major role as intermediate host and may transmit to humans • May be lethal in cats, 3 of 5 infected cheetahs died in a British zoo in the 70’s Molluscum Contagiosum • Caused by the only member of the Molluscipoxvirus genus, Molluscum Contagiosum Virus • Antigenically distinct from orthopoxviruses • First...
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