Creatine Supplementation

Subjects lifted three timesweek and consumed drinks

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Unformatted text preview: ts lifted three times/week and consumed drinks that contained either 5g of Cr in 250mL of Gatorade1 following a 5-day loading period of 7g Cr/day, 35g of protein in 250mL Gatorade, or a combination of 5g Cr and 35g protein in 250mL Gatorade, or 250mL Gatorade. 3.2 Renal and Liver Function It has been established that studies that have investigated renal function following Cr supplementation by assessing urinary creatinine clearance have found no indication of impaired function;[18,67-72] however, it has been suggested that care should be taken if an individual has a pre-existing compromised renal function.[14] There is no scientific evidence that liver function is impaired by either short-term, high-dosage Cr ingestion or longer term, low-dosage programmes.[8,73-76] 1 3.3 Muscle Cramping Most reports of muscle cramping following Cr supplementation have been anecdotal in nature and unsubstantiated, especially when research designs have included control groups and blinding. There is no direct evidence that Cr supplementation can induce muscle cramping and that if cramps are experienced that it is most likely due to either the high intensity of the workout[8,9,18] or to a disruption in electrolyte balance. Most authors agree that adequate hydration during exercise is likely to significantly reduce the chance of getting muscle cramps. 3.4 Body Mass/Water Retention The early changes observed in BW following Cr ingestion is probably explained by increases in body water, especially in the intracellular compartments (within the muscle cell). Authors have speculated that the reason for the increase in intracellular water is the increased osmotic load associated with the increased Cr concentrations within the cell.[9,26,77,78] This does have implications for body composition measurements taken in conjunction with resistance training studies. Increases in muscle cross-sectional area may be attributed to increased muscle hypertrophy whereas the increase in size may be primarily due to intracellular water retention. These same...
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This note was uploaded on 01/28/2014 for the course BI 231 taught by Professor Richardmay during the Fall '13 term at Southern Oregon.

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