quiz4.docx - 1 The increased rate of glucose uptake by...

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1. The increased rate of glucose uptake by cancer cells relative to normal cell is employed in a posiron emission tomography based diagnosis and monitoring of cancer. True 2. Aerobic glycolysis is a major source of ATP generation for cancer cell metabolism. True 3. The most significant substrates for energy supply and metabolism in cancer cells are glucose and _________ ? Glucose and Glutamine 4. The supply of macronutrients to rapidly proliferating malignant cells requires the availability of? Glucose 5. Cancer cells exhibit cell autonomous regulation of metabolism that is independent of growth factor signaling to promote proliferation and survival. True or false? 6. What metabolic intermediates is provided to proliferating cells by the pentose phospate pathway? The two most important product synthesized in Penrose phosphate pathway is 1.Ribose-5- Phosphate 2.NADPH 7. Describe the significance of glutamine in cancer cells? glutamine is an a major amino acid found in plasma. It is used by cancer cells for growth and protection

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