Unformatted text preview: ne is derived must have
been created for reproductive purposes but is
subsequently discarded and must not have had
the possibility of developing further as a human
• Informed consent allowing the donation of the embryo and subsequent ownership of it.
• Policies governing the use of the stem cell lines. Technically: Human embryonic stem cell
(hESC) research has the potential to allow better
understanding of normal cell development and
subsequently the possible correction of serious
medical conditions such as cancer and birth defects.
Another potential application of stem cells is in
making replacement cells and tissues for therapeutic
purposes e.g. in treating Parkinson's and Alzheimer's
diseases, spinal cord injury, stroke, burns, heart
disease, diabetes, osteoarthritis and rheumatoid
arthritis. Using hESCs poses formidable technical
challenges as scientists must learn to control the
development of pluripotent stem cells into all the
different types of body cells and overcome the threat
of rejection by the patient's immune system. Adult
stem cell research is not new whereas hESC research
is still in its infancy, lacking funding and support, and
there may even be laws banning it in some countries. See BioLinks under Biotechnology > Applications in
Biotechnology > Cloning and Tissue Culture on
Biozone's web site for further information on this topic. Monoclonal Antibodies (page 151) 1.
2. Biozone International 2009 Photocopying Prohibited B-lymphocytes. Tumor cells are immortal and, when they fused with
B lymphocytes, the resulting hybridomas acquire the Anatomy and Physiology AGAINST
• Organ donation can only take place under certain circumstances (e.g. accident and brain death,
or death while in intensive care). Donor must be
medically and legally dead.
• Despite advances, transplant recipients face several (avoidable) risks, including inappropriate
selection and testing of donors and inadequate
sterilization of some tissues. These increase the
risk of infection, e.g. from prions, malignancies,
and viruses such as West Nile. There is also the
risk that the material for transplantation may be of
poor quality (...
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This document was uploaded on 01/28/2014.
- Winter '13